>>Signaling Pathways>> PROTAC>> E3 Ligase Ligand-Linker Conjugate>>Thalidomide-NH-C6-NH2 TFA

Thalidomide-NH-C6-NH2 TFA

Catalog No.GC39513

탈리도마이드-NH-C6-NH2 TFA는 탈리도마이드 기반 세레블론 리간드와 PROTAC 기술에 사용되는 링커를 통합하는 합성된 E3 리가제 리간드-링커 접합체입니다.

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Thalidomide-NH-C6-NH2 TFA Chemical Structure

Cas No.: 2093386-51-5

Size 가격 재고 수량
100mg
US$510.00
재고 있음
250mg
US$908.00
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500mg
US$1,251.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

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