Laurdan |
| Catalog No.GC18338 |
Laurdan es una sonda fluorescente permeable a la membrana que muestra sensibilidad espectral a la fase de fosfolípidos de la membrana celular a la que está unida.
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Cas No.: 74515-25-6
Sample solution is provided at 25 µL, 10mM.
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound.[1] Quantitation of generalized polarization (GP) of laurdan can be used to identify phospholipid phase. When excited at 340 nm, GP values are 0.6 and -0.2 for gel phase and liquid crystalline phase, respectively. GP does not change with polar head group or pH (in the range 4-10); it changes only with phase state.
Reference:
[1]. Parasassi, T., De Stasio, G., Ravagnan, G., et al. Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence. Biophys. J. 60(1), 179-189 (1991).
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