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(±)12-HETE (Synonyms: (±)-Hydroxyeicosatetraenoic Acid)

Katalog-Nr.GC40429

(±) 12-HETE, ein wichtiges Stoffwechselprodukt der Arachidonsäure unter Verwendung von 12-LOX-Katalyse, hemmt die Zellapoptose dosisabhängig.

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(±)12-HETE Chemische Struktur

Cas No.: 71030-37-0

Größe Preis Lagerbestand Menge
25μg
100,00 $
Auf Lager
50μg
188,00 $
Auf Lager
100μg
358,00 $
Auf Lager
250μg
795,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers . It aggregates neutrophils with an EC50 value of 40 nM.[1] 

Reference:
[1]. O'Flaherty, J.T., Thomas, M.J., Lees, C.J., et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. American Journal of Pathology 104, 55-62 (1981).

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