Metabolism
- Sterol Biosynthesis(41)
- PPAR(217)
- 5-alpha Reductase(10)
- 5-Lipoxygenase(11)
- Aminopeptidase(9)
- Adenosine Deaminase(6)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(65)
- CETP(9)
- Cholesterol absorption(1)
- CPT1(2)
- CYP3A/CYP450(22)
- Dehydrogenase(132)
- DHFR(7)
- DGAT(8)
- Dopamine β-hydroxylase(10)
- Enolase(12)
- FAAH(37)
- Factor Xa(61)
- Ferroptosis(193)
- Folate Analogue(2)
- Glucokinase(18)
- HLE(0)
- HMG-CoA Reductase(37)
- HSP(69)
- IDO(46)
- KRAS-PDEδ(3)
- MAO(6)
- Metabolic Enzymes(6)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(25)
- P450(138)
- PDE(245)
- Phospholipase(130)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(19)
- SGLT(29)
- TPH(4)
- Transferase(177)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(36)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(1)
- Thioredoxin Reductase(0)
- Catalase(15)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(103)
- Pyruvate kinase(13)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(13)
- Bile Acids & Microbiome(131)
- Bone Growth & Remodeling(55)
- Carbohydrate Metabolism(166)
- Cofactors & Vitamins(87)
- Dyslipidemias(109)
- Inborn Errors of Metabolism(100)
- Metabolic Syndrome(22)
- Necroptosis(12)
- Necrosis(19)
- Nutrient Sensing(14)
- Phosphodiesterase(34)
- Reproductive Biology(184)
- Thermogenesis(10)
- Prolyl Hydroxylation Enzymes(2)
- Biliary System(16)
- Metabolic Disease(5)
- Fat Mass and Obesity-associated Protein (FTO)(5)
- SHIP(1)
- Liposome(8)
- MetAP(0)
- PGC-1α(8)
- PI5P4K(1)
- FOXO(0)
- Furin(1)
- Metabolic Diseases(2)
Produkte für Metabolism
- Bestell-Nr. Artikelname Informationen
-
GC19910
2,2',4,4'-Tetrabromodiphenyl Ether
BDE-47
-
GC19941
DL-Leucic Acid
-
GC66197
α-?Terpinyl acetate
α-Terpinylacetat ist ein Monoterpenester, der aus dem Ätherischen Öl von Laurus nobilis L. isoliert wird. α-Terpinylacetat ist ein kompetitives P450 2B6-Substrat, das mit einem Kd-Wert von 5,4&7#956 an das aktive Zentrum von P450 2B6 bindet;M.
-
GC11123
α-CEHC
γTocopherol Metabolite, GTM, 2,7,8trimethyl2(βCarboxyEthyl)6Hydroxychroman
A major metabolite of δ-tocopherol -
GC48276
α-Cyclodextrin (hydrate)
α-CD, NSC 269470, Schardinger α-Dextrin
A cyclic hexasaccharide -
GC48277
α-D-Glucose-1,6-bisphosphate (cyclohexyl ammonium salt hydrate)
D-Glucose-1,6-diphosphate, Glc-1,6-P2
A neuropeptide with diverse biological activities -
GC48278
α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
D-Glucose-1,6-diphosphate
A bis-phosphorylated derivative of α-D-glucose -
GC48279
α-D-Glucose-1-phosphate (sodium salt hydrate)
α-D-Glc 1-P
An intermediate in glycogen metabolism -
GC52253
α-Enolase (1-19)-biotin Peptide
Enolase-1 (1-19)-biotin
A biotinylated α-enolase peptide -
GC45208
α-hydroxy Metoprolol
α-hydroxy Metoprolol is an active metabolite of the β1-adrenergic receptor blocker metoprolol.
-
GC45210
α-Linolenic Acid (sodium salt)
ALA, C18:3 (9Z,12Z,15Z), C18:3 n-3
α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. -
GC48283
α-Linolenic Acid-d14
ALAd14
An internal standard for the quantification of αLinolenic acid -
GC45602
α-Linolenic Acid-d5 MaxSpec• Standard
ALA-d5, C18:3 (9Z,12Z,15Z)-d5, C18:3 n-3-d5
-
GC49008
α-Muricholic Acid-d4
ω-MCA-d4
An internal standard for the quantification of α-muricholic acid -
GC40480
α-Phenyl-α-(2-pyridyl)acetonitrile
NSC 16276, 2-Pyridylphenylacetonitrile
α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion. -
GC45226
β-BHC
β-HCH, β-Hexachlorocyclohexane, β-Lindane
β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane. -
GC90496
β-Cortolone
Ein Stoffwechselprodukt von Cortisol.
-
GC48297
β-Cyclodextrin (hydrate)
β-CD, NSC 269471, NSC 314334, Schardinger β-Dextrin
A cyclic hexasaccharide -
GC45232
β-D-Glucosamine Pentaacetate
N-Acetyl-β-D-Glucosamine tetraacetate, NSC 224432
β-D-Glucosamine pentaacetate is an N-acetylglucosamine derivative that has been shown to promote hyaluronic acid production. -
GC49769
β-Glucogallin
1-O-Galloyl-β-D-glucose
A plant metabolite and an aldose reductase 2 inhibitor -
GC49890
β-Glycerophosphate-d5 (sodium salt hydrate)
Glycerol 2-Phosphate-d5
An internal standard for the quantification of β-glycerophosphate -
GC49647
β-Hyodeoxycholic Acid (hydrate)
3β,6α-dihydroxy-5β-Cholan-24-oic Acid, isoHDCA, Isohyodeoxycholic Acid
A 3β epimer of hyodeoxycholic acid -
GC49007
β-Muricholic Acid-d4
ω-MCA-d4
An internal standard for the quantification of β-muricholic acid -
GC41502
β-Myrcene
NSC 406264
β-Myrcen (β-β-Myrcen), eine aromatische flüchtige Verbindung, unterdrückt die TNFα-induzierte NF-κB-Aktivität. -
GC40551
γ-CEHC
γTocopherol Metabolite, GTM, 2,7,8trimethyl2(βCarboxyEthyl)6Hydroxychroman
The major tocopherol obtained from natural dietary sources is γ-tocopherol, whereas α-tocopherol is the form of Vitamin E typically obtained from synthetic supplements. -
GC52400
γ-Glu-Ala (trifluoroacetate salt)
γ-Glutamylalanine, γ-L-Glutamyl-L-alanine
A dipeptide -
GC52404
γ-Glu-Phe (trifluoroacetate salt)
γ-Glutamylphenylalanine
A dipeptide with metabolism-altering activity -
GC41596
δ-CEHC
γTocopherol Metabolite, GTM, 2,7,8trimethyl2(βCarboxyEthyl)6Hydroxychroman
Molecules having vitamin E antioxidant activity include four tocopherols (α, β, γ, δ) and four tocotrienols (α, β, γ, δ). -
GC45239
δ4-Abiraterone
CB 7627, D4A
δ4-Abirateron ist ein Hauptmetabolit von Abirateron. δ4-Abirateron ist ein Inhibitor von CYP17A1, 3b-Hydroxysteroiddehydrogenase (3βHSD) und Steroid-5a-Reduktase (SRD5A) und auch ein Antagonist des Androgenrezeptors. -
GC15975
α-Estradiol
Alfatradiol, α-Estradiol, 17-epi Estradiol, NSC 20293, 17α-Oestradiol
α-Estradiol ist ein schwaches Östrogen und ein 5&7#945;-Reduktasehemmer, der als topisches Medikament bei der Behandlung von androgener Alopezie verwendet wird. -
GC40720
ω-Muricholic Acid
ω-MCA
ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.[1],[2] It is formed via enzymatic conversion of β-MCA by a variety of intestinal microorganisms, including Clostridium, in rat and mouse gut.
-
GC49009
ω-Muricholic Acid-d4
ω-MCA-d4
An internal standard for the quantification of ω-MCA -
GC49296
τ-Fluvalinate
tau-Fluvalinate
A pyrethroid acaricide -
GC46314
(±)-β-Hydroxybutyrate-d4 (sodium salt)
βHydroxybutanoic Acidd4
An internal standard for the quantification of (±)βhydroxybutyrate -
GC52010
(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid
αHYA, (±)-10-hydroxy-12(Z),15(Z)-ODE
An oxylipin gut microbiota metabolite -
GC52013
(±)-10-hydroxy-12(Z)-Octadecenoic Acid
10-hydroxy-cis-12-Octadecenoic Acid
An oxylipin and metabolite of linoleic acid -
GC52421
(±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5
10-hydroxy-cis-12-Octadecenoic Acid-d5
An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid -
GC41661
(±)-4-hydroxy Propranolol β-D-Glucuronide
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
-
GC45277
(±)-Camphene
DL-Camphene, NSC 4165
-
GC46284
(±)-Cotinine-d3
An internal standard for the quantification of cotinine
-
GC41671
(±)-Equol 4'-sulfate (sodium salt)
R,S-Equol 4'-Sulfate
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
-
GC41315
(±)-Ketoprofen Glucuronide
rac-Ketoprofen Acyl-β-D-glucuronide, (R,S)-Ketoprofen Glucuronide
(±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen.
-
GC91298
(±)-Linalool-d3
Eine interne Norm für die Quantifizierung von (±)-Linalool.
-
GC40954
(±)-N-3-Benzylnirvanol
(S)-N-3-benzyl Nirvanol
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol. -
GC49875
(±)-N-desmethyl Venlafaxine (hydrochloride)
Wy 45494
A minor active metabolite of venlafaxine -
GC39271
(±)-Naringenin
SDihydrogenistein, NSC 11855, NSC 34875, Salipurol
(±)-Naringenin ist ein natürlich vorkommendes Flavonoid. -
GC45618
(±)-trans-GK563
GK563
A GVIA iPLA2 inhibitor -
GC40802
(±)12(13)-DiHOME
Isoleukotoxin diol
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
-
GC40270
(±)5(6)-DiHET
(±)5,6-DiHETrE
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
-
GC40271
(±)5(6)-DiHET MaxSpec® Standard
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
-
GC40440
(±)8(9)-EET
(±)8,9EpETrE
(±)8(9)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid. -
GC40838
(±)8(9)-EET methyl ester
(±)8,9EpETrE methyl ester
(±)8(9)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. -
GC46264
(±)8(9)-EET-d11
(±)8,9-EET-d11, (±)8,9-EpETrE-d11
A neuropeptide with diverse biological activities -
GC45921
(±)8(9)-EET-d11 methyl ester
(±)8,9-EpETrE-d11 methyl ester
A neuropeptide with diverse biological activities -
GC40282
(+)-5-trans Cloprostenol
DCloprostenol, (+)5,6trans Cloprostenol, (+)5trans16mchlorophenoxy tetranor PGF2α, (+)5trans16mchlorophenoxy tetranor Prostaglandin F2α
Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. -
GC45260
(+)-Cloprostenol isopropyl ester
(+)-5-cis Cloprostenol isopropyl ester, (+)16mchlorophenoxy tetranor Prostaglandin F2α isopropyl ester
(+)-Cloprostenolisopropylester, ein Prostaglandin F2α Analoga, ist das Zwischenprodukt von (+)-Cloprostenol. -
GC45261
(+)-Cloprostenol methyl amide
DCloprostenol methyl amide, (+)16mChlorophenoxy tetranor PGF2α methyl amide
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). -
GC45262
(+)-Cloprostenol methyl ester
DCloprostenol methyl ester, (+)16mChlorophenoxy tetranor PGF2α methyl ester
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). -
GC45264
(+)-Geodin
(+)-Geodin, ein Pilzmetabolit, zeigt antibakterielle Aktivität.
-
GC12404
(+)-Ketoconazole
R 41400
(+)-Ketoconazol ((+)-R 41400) ist ein Imidazol-Antimykotikum, ein CYP3A4-Hemmer. -
GC30424
(-)-Cephaeline dihydrochloride (NSC 32944)
(-)-Cephaelindihydrochlorid (NSC 32944) ist ein selektiver CYP2D6-Inhibitor mit einem IC50-Wert von 121 μM.
-
GC18343
(-)-CP 55,940
(-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively.
-
GC14049
(-)-Epigallocatechin gallate (EGCG)
EGCG
Ein Phenol mit vielfältigen biologischen Aktivitäten.
-
GC45248
(-)-FINO2
(-)-FINO2 ist ein potenter Ferroptose-Induktor. (-)-FINO2 hemmt die AktivitÄt von GPX4. (-)-FINO2 ist ein stabiles Oxidationsmittel, das Eisen oxidiert und bei unterschiedlichen pH-Werten stabil ist. (-)-FINO2 verursacht eine weit verbreitete Lipidperoxidation.
-
GC14520
(-)-p-Bromotetramisole Oxalate
(-)-p-Bromotetramisole, L-para-Bromotetramisole
ALP-Inhibitor, potent und unspezifisch
-
GC45252
(-)-Sitagliptin Carbamoyl Glucuronide
(R)-Sitagliptin Carbamoyl Glucuronide
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. -
GC17102
(-)-Tetramisole
NSC 177023, R 12654, L-Tetramisole
Levamisol ((-)-Tetramisol)-Hydrochlorid ist ein Anthelminthikum und Immunmodulator, das zu einer Klasse synthetischer Imidazothiazol-Derivate gehÖrt. -
GC18622
(2'S)-Nicotine-1-oxide
Nicotine-N-oxide
(2'S)-Nicotine-1-oxide is a metabolite of nicotine . -
GC41691
(2R)-Glycerol-O-β-D-galactopyranoside
3-O-β-D-Galactopyranosyl-sn-glycerol
(2R)-Glycerol-O-β-D-Galactopyranosid (3-O-β-D-Galactopyranosyl-sn-glycerol) ist ein gutes Substrat fÜr alle drei Komponenten des lac-Operons, d. -
GC46330
(2R)-Octyl-α-hydroxyglutarate-d17
(2R)Octyl2-HG-d17
A neuropeptide with diverse biological activities -
GC46332
(2S)-Octyl-α-hydroxyglutarate-d17
(2S)-Octyl-2-HG-d17
A neuropeptide with diverse biological activities -
GC49690
(3R,5R)-Rosuvastatin (calcium salt)
A potential impurity found in bulk preparations of rosuvastatin
-
GC41694
(3S)-hydroxy Quinidine
(3S)-hydroxy Quinidine is an active quinidine metabolite.
-
GC60396
(3S,5R)-Fluvastatin sodium
(3S,5R)-Fluvastatin-Natrium ((3S,5R)-XU 62-320) ist das (3S,5R)-Enantiomer von Fluvastatin.
-
GC68317
(3S,5R)-Fluvastatin-d6 sodium
(3S,5R)-XU 62-320 D6
-
GC13751
(3S,5S)-Atorvastatin (sodium salt)
negetive control of Atorvastatin, HMG-CoA reductase inhibitor
-
GC46333
(4′-Hydroxy)phenoxybenzoic Acid
A pyrethroid insecticide metabolite
-
GC48508
(4-Carboxybutyl-d4)triphenylphosphonium (bromide)
TPP-d4, 5-Triphenylphosphoniovaleric Acid-d4
An internal standard for the quantification of (4-carboxybutyl)triphenylphosphonium -
GC41695
(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)
Tetrahydrofolate, THFA
(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism. -
GC41088
(6S)-Tetrahydrofolic Acid
(6S)-Tetrahydrofolic acid is a diastereomer of tetrahydrofolic acid, a reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.
-
GC34980
(E)-Ferulic acid
(E)-FerulasÄure ist ein Isomer von FerulasÄure, einer aromatischen Verbindung, die in PflanzenzellwÄnden reichlich vorhanden ist. (E)-FerulasÄure verursacht die Phosphorylierung von β-Catenin, was zu einem proteasomalen Abbau von β-Catenin fÜhrt und die Expression des pro-apoptotischen Faktors Bax erhÖht und die Expression des ÜberlebensfÖrdernden Faktors Survivin verringert. (E)-FerulasÄure zeigt eine starke FÄhigkeit, reaktive Sauerstoffspezies (ROS) zu entfernen und die Lipidperoxidation zu hemmen. (E)-FerulasÄure Übt sowohl Antiproliferations- als auch Antimigrationswirkungen in der menschlichen Lungenkrebszelllinie H1299 aus.
-
GC91418
(E)-KPT-330
KTP-330; trans Selinexor
(E)-KPT-330 ist ein Metabolit des Exportin 1 (XPO1/CRM1) Inhibitors Selinexor.
-
GC40286
(E,Z)-2-propyl-2-Pentenoic Acid
2-propyl-2-Pentenoate, 2-propylpenten-2-oic Acid, 2-ene-VPA
(E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity. -
GC49189
(E/Z)-4-hydroxy Tamoxifen-d5
Afimoxifene-d5, 4-OHT-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen -
GC91543
(E/Z)-Droloxifene
3-Hydroxytamoxifen
(E/Z)-Droloxifene is a mixture of (E)-droloxifene, a selective estrogen receptor modulator (SERM), and (Z)-droloxifene. -
GA11210
(H-Cys-OH)2
(–)-Cystine, NSC 13203
-
GC74692
(R)-(+)-Aminoglutethimide
d-Aminoglutethimide
(R)-(+)-Aminoglutethimide ist ein starker und oral aktiver Aromatasehemmer. -
GC34984
(R)-(-)-Rolipram
(R)-(–)-Rolipram, (R)-Rolipram
(R)-(-)-Rolipram ist das R-Enantiomer von Rolipram. -
GC91125
(R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-carboxylic Acid
Ein Zwischenprodukt in der Synthese von Ervogastat.
-
GC25001
(R)-Avanafil
R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM.
-
GC40678
(R)-Bromoenol lactone
(R)BEL
(R)-Bromenollacton ((R)-BEL) ist ein irreversibler, chiraler, Mechanismus-basierter Inhibitor der Calcium-unabhÄngigen Phospholipase γ (iPLA2γ). -
GC46342
(R)-Bromoenol lactone-d7
(R)BELd7
A neuropeptide with diverse biological activities -
GC52290
(R)-HTS-3
An inhibitor of LPCAT3
-
GC70609
(R)-IDO/TDO-IN-1
(R)-IDO/TDO-IN-1 Verbindung 25 ist ein Indoleamin-2,3-Dioxygenase IDO Inhibitor mit guten pharmakokinetischen Eigenschaften.
-
GC67864
(R)-Irsenontrine
(R)-E2027
-
GC41722
(R,S)-Carvedilol Glucuronide
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.
-
GC61548
(Rac)-5-Keto Fluvastatin
(Rac)-5-Keto-Fluvastatin (3-Hydroxy-5-Keto-Fluvastatin) ist eine Verunreinigung von Fluvastatin (XU 62320).
-
GC39799
(Rac)-Brassinazole
A brassinosteroid biosynthesis inhibitor
-
GC62743
(Rac)-EC5026
(Rac)-BPN-19186
(Rac)-EC5026 ((Rac)-BPN-19186) ist ein potenter Piperidin-Inhibitor der lÖslichen Epoxidhydrolase (sEH), extrahiert aus Patent WO2019156991A1, Seite 39, hat einen Ki von 0,06 nM. -
GC69796
(Rac)-Etavopivat
(Rac)-FT-4202
(Rac)-Etavopivat((Rac)-FT-4202) ist ein Isomer von Etavopivat. Etavopivat ist ein oral aktiver Aktivator der Pyruvatkinase-R (PKR) in roten Blutkörperchen mit einer therapeutischen Wirkung bei Sichelzellanämie und anderen Hämoglobinopathien, die zur Forschung verwendet werden können.