2-Aminoimidazole |
| Katalog-Nr.GC61639 |
2-Aminoimidazol ist ein wirksames Antibiofilm-Mittel, das als Adjuvans fÜr antimikrobielle Mittel verwendet werden kann.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7720-39-0
Sample solution is provided at 25 µL, 10mM.
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2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM[1][2][3].
[1]. Thompson RJ, et, al. Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-Aminoimidazole-based antibiofilm agent. Biochemistry. 2012 Dec 11;51(49):9776-8. [2]. Jacobs L, et, al. 2-Aminoimidazoles as potent inhibitors of contaminating brewery biofilms. Biofouling. 2021 Feb 11;1-17. [3]. Ilies M, et, al. 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J Med Chem. 2010 May 27;53(10):4266-76.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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