4-Methylumbelliferyl-β-D-N,N',N''-Triacetylchitotrioside (Synonyms: MUF-triNAG) |
| Katalog-Nr.GC42452 |
4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotriosid ist ein fluorogenes Substrat für Chitinase und Chitotriosidase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 53643-13-3
Sample solution is provided at 25 µL, 10mM.
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4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is a fluorogenic substrate for chitinases and chitotriosidases. 4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is cleaved by chitinases and chitotriosidases to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to screen plasma samples for reduced chitotriosidase activity that may be indicative of lysosomal storage disorders.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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