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Atibeprone (Synonyms: Atibeprone; Lu 53439; Lu-53439; Lu53439;)

Katalog-Nr.GB62227 Copy One-Click Copy Product Info

Atibeprone, also known as Lu 53439, is MAO-B inhibitor.

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Atibeprone Chemische Struktur

Cas No.: 153420-96-3

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1mg
90,00 $
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5mg
350,00 $
Auf Lager
10mg
550,00 $
Auf Lager
25mg
1.250,00 $
Auf Lager
50mg
1.950,00 $
Auf Lager
100mg
3.250,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.



Description of Atibeprone

Atibeprone, also known as Lu 53439, is MAO-B inhibitor. The anticonvulsant activity of inhibitors of monoamine oxidase (MAO) was reported early after the development of irreversible MAO inhibitors such as tranylcypromine, but was never clinically used because of the adverse effects of these compounds. In contrast to esuprone and L-deprenyl, the selective MAO-B inhibitor LU 53439 was not effective in the kindling model; this substantiates the previous notion that the anticonvulsant activity of L-deprenyl is not related to MAO-B inhibition, but to other effects of this drug, such as inhibition of MAO-A.

Chemical Properties of Atibeprone

Cas No. 153420-96-3 SDF
Überlieferungen Atibeprone; Lu 53439; Lu-53439; Lu53439;
Canonical SMILES CC1=C(C)C(OC2=C1C=CC(OCC3=NN=C(C(C)C)S3)=C2)=O
Formula C17H18N2O3S M.Wt 330.402
Löslichkeit To be determined Storage Store at-20℃
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Atibeprone

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.0266 mL 15.1331 mL 30.2662 mL
5 mM 605.3 μL 3.0266 mL 6.0532 mL
10 mM 302.7 μL 1.5133 mL 3.0266 mL
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In vivo Formulation Calculator (Clear solution) of Atibeprone

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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