BMS-8 |
| Katalog-Nr.GC42957 |
BMS-8 hemmt die PD-1/PD-L1-Interaktion mit IC50 von 7,2 μM. BMS-8 bindet direkt an PD-L1 und induziert die Bildung von PD-L1-Homodimeren, was wiederum die Wechselwirkung mit PD-1 verhindert.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1675201-90-7
Sample solution is provided at 25 µL, 10mM.
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BMS-8 is a small molecule inhibitor of the interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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