BOP |
| Katalog-Nr.GC50325 |
BOP ist ein potenter und selektiver dualer &7#945;9β1/α4β1 Integrin-Inhibitor mit Kd-Werten im pikomolaren Bereich.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1947348-42-6
Sample solution is provided at 25 µL, 10mM.
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Dual α9β1/α4β1 integrin inhibitor; rapidly and preferentially mobilizes HSCs and progenitors. Augments HSC mobilization in combination with AMD3100 . High affinity fluorescent derivative R-BC154 also available.
Cao et al (2014) Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vi Org.Biomol.Chem. 12 965 PMID:24363056 |Pepinsky et al (2002) Comparative assessment of the ligand and metal ion binding properties of integrins α9β1 and α4β1. Biochemistry 41 7125 PMID:12033947 |Cao et al (2016) Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat.Commun. 7 11007 PMID:26975966
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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