Burixafor hydrobromide (TG-0054 hydrobromide) (Synonyms: TG-0054 hydrobromide) |
| Katalog-Nr.GC30625 |
Burixafor-Hydrobromid (TG-0054-Hydrobromid) (TG-0054-Hydrobromid) ist ein oral bioverfÜgbarer und potenter CXCR4-Antagonist und ein gut antiangiogenes Medikament, das bei der Behandlung von Chorioidea-Neovaskularisation von potenziellem Wert ist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1191450-19-7
Sample solution is provided at 25 µL, 10mM.
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Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization[1]. Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction[2].
[1]. Shelke NB, et al. Intravitreal Poly(L-lactide) Microparticles Sustain Retinal and Choroidal Delivery of TG-0054, a Hydrophilic Drug Intended for Neovascular Diseases. Drug Deliv Transl Res. 2011 Feb;1(1):76-90. [2]. Hsu WT, et al. CXCR4 Antagonist TG-0054 Mobilizes Mesenchymal Stem Cells, Attenuates Inflammation, and Preserves Cardiac Systolic Function in a Porcine Model of Myocardial Infarction. Cell Transplant. 2015;24(7):1313-28.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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