Buserelin-NHNH2 (trifluoroacetate salt) |
| Katalog-Nr.GC42991 |
Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH. It is a long-acting agent that, after an initial increase in sex hormone levels, decreases the level of circulating gonadotropins and sex hormones. Buserelin (20 µg/kg) reduces tumor growth in a DMBA-induced rat model of mammary cancer. It induces enteric neurodegeneration, decreasing the number of luteinizing hormone receptor-positive neurons in the rat gastrointestinal tract, when administered at a dose of 1 mg/kg for 5 days. Formulations containing buserelin have been used in the treatment of hormone-dependent prostate cancer and endometriosis.
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