2-(Isopentylamino)naphthalene-1,4-dione |
| Katalog-Nr.GC46505 |
A vitamin K analog
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1607447-79-9
Sample solution is provided at 25 µL, 10mM.
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2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1 It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).
1.Li, X., Himes, R.A., Prosser, L.C., et al.Discovery of the first vitamin K analogue as a potential treatment of pharmacoresistant seizuresJ. Med. Chem.63(11)5865-5878(2020)
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