Acetyl Hexapeptide-3 (acetate) (Synonyms: Ac-EEMQRR-NH2, Acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2, Acetyl Hexapeptide-8) |
| Katalog-Nr.GC46786 |
A synthetic hexapeptide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Acetyl hexapeptide-3 is a synthetic acetylated and amidated hexapeptide consisting of amino acid residues 12-17 of synaptosomal-associated protein 25 (SNAP-25).1 It inhibits formation of the SNARE complex in vitro in a concentration-dependent manner. It also inhibits calcium-induced norepinephrine release in permeabilized chromaffin cells (IC50 = 110 μM). Acetyl hexapeptide-3 (10% in an oil-and-water emulsion) inhibits decreases in type I collagen levels and skin thickness, as well as increases in type III collagen levels, in skin in a mouse model of subacute aging induced by D-galactose when administered topically.2
1.Blanes-Mira, C., Clemente, J., Jodas, G., et al.A synthetic hexapeptide (argireline) with antiwrinkle activityInt. J. Cosmet. Sci.24(5)303-310(2002) 2.Wang, Y., Wang, M., Xiao, X.S., et al.The anti-wrinkle efficacy of argirelineJ. Cosmet Laser Ther.15(4)237-241(2013)
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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