C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) (Synonyms: N-omega-CD3-Octadecanoyl monosialoganglioside GM1-d3, N-CD3-Stearoyl-GM, C18 GM1-d3, GM1 (18:1/18:0-d3), GM1 (d18:1/C18:0)-d3, Monosialoganglioside GM1-d3, N-Stearoyl Monosialoganglioside GM1-d3)

Name: C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt)
Brand: GlpBio
SKU: GC46992
Availability: InStock
Rating: 5 (7 reviews)

Katalog-Nr.GC46992

A neuropeptide with diverse biological activities

Products are for research use only. Not for human use. We do not sell to patients.

C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) Chemische Struktur

Cas No.: N/A

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Menge

500 μg

942,00 $

Auf Lager

Tel：(909) 407-4943 Email: sales@glpbio.com

Kundenbewertungen

Basiert auf Kundenrezensionen.

Sample solution is provided at 25 µL, 10mM.

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Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >99.00%

C18 Ganglioside G_M1-d₃ (d18:1/18:0-d₃) is intended for use as an internal standard for the quantification of C18 ganglioside G_M1. Ganglioside G_M1 is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.^1,2 C18 Ganglioside G_M1 is found in the brain, primarily in the piriform cortex, amygdala nucleus, striatum, and hippocampal CA1 region.³ The ratio of C18 ganglioside G_M1 (d20:1/18:0) to C18 ganglioside G_M1 is decreased in the outer molecular layer of the hippocampal dentate gyrus in postmortem tissue from patients with Alzheimer's disease.⁴ [Matreya, LLC. Catalog No. 2050]

1.Kolter, T.Ganglioside biochemistryISRN Biochem.506160(2012) 2.Mocchetti, I.Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophinsCell Mol. Life Sci.62(19-20)2283-2294(2005) 3.Andres, A.D., Young, L.E.A., Gentry, M.S., et al.Spatial profiling of gangliosides in mouse brain by mass spectrometry imagingJ. Lipid Res.(2020) 4.Hirano-Sakamaki, W., Sugiyama, E., Hayasaka, T., et al.Alzheimer's disease is associated with disordered localization of ganglioside GM1 molecular species in the human dentate gyrusFEBS Lett.589(23)3611-3616(2015)

Cas No.	N/A	SDF
Überlieferungen	N-omega-CD3-Octadecanoyl monosialoganglioside GM1-d3, N-CD3-Stearoyl-GM, C18 GM1-d3, GM1 (18:1/18:0-d3), GM1 (d18:1/C18:0)-d3, Monosialoganglioside GM1-d3, N-Stearoyl Monosialoganglioside GM1-d3
Canonical SMILES	OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@@]2([H])[C@@H]([C@@]([C@H]([C@H](O2)CO)O[C@]3([H])O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)O[C@@]4([H])[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)O)O)CO)([H])O[C@]5(C([O-])=O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@@H]([C@H](O)CO)O)O5)O)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC([2H])([2H])[2H])=O.[NH4+]
Formula	C73H127D3N3O31.NH4	M.Wt	1566.9
Löslichkeit	Chloroform:Methanol:Water (2:1:0.1): Soluble	Storage	Store at -20°C, protect from light
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	0.6382 mL	3.191 mL	6.382 mL
	5 mM	0.1276 mL	0.6382 mL	1.2764 mL
	10 mM	0.0638 mL	0.3191 mL	0.6382 mL

Molaritätsrechner
Verdünnung-Rechner

Berechnen

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal:μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Bewertungen

Review for C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt)

Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) (Synonyms: N-omega-CD3-Octadecanoyl monosialoganglioside GM1-d3, N-CD3-Stearoyl-GM, C18 GM1-d3, GM1 (18:1/18:0-d3), GM1 (d18:1/C18:0)-d3, Monosialoganglioside GM1-d3, N-Stearoyl Monosialoganglioside GM1-d3)

Kundenbewertungen

GlpBio Citations

Bioactive Compounds Premium Provider

GlpBio Produkte in seriösen Veröffentlichungen zitiert

Product Documents

Quality Control & SDS

Complete Stock Solution Preparation Table

Molaritätsrechner

Verdünnung-Rechner

In vivo Formulation Calculator (Clear solution)

Bewertungen