CAY10641 |
Katalog-Nr.GC47049 |
An inactive alcohol derivative of a highly potent cPLA2 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1233706-89-2
Sample solution is provided at 25 µL, 10mM.
Cytosolic phospholipase A2α (cPLA2α) specifically catalyzes the hydrolysis of arachidonic acid from the sn-
1.Schaloske, R.H., and Dennis, E.A.The phospholipase A2 superfamily and its group numbering systemBiochemica et Biophysica Acta17611246-1259(2006) 2.Drews, A., Bovens, S., Roebrock, K., et al.1-(5-carboxyindol-1-yl)propan-2-one inhibitors of human cytosolic phospholipase A2α with reduced lipophilicity: Synthesis, biological activity, metabolic stability, solubility, bioavailability, and topical in vivo activityJournal of Medicinal Chemistry535165-5178(2010)
Average Rating: 5
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