Fenbendazole-d3 (Synonyms: Methyl 5-(phenylthio)-2-benzimidazolecarbamate-d3) |
| Katalog-Nr.GC47334 |
Fenbendazol-d3 ist ein mit Deuterium gekennzeichnetes Fenbendazol.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1228182-47-5
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Fenbendazole-d3 is intended for use as an internal standard for the quantification of fenbendazole by GC- or LC-MS. Fenbendazole is a benzimidazole anthelmintic.1 It is active against Giardia in vitro (IC50 = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection.2 It also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro.3
1.Morgan, U.M., Reynoldson, J.A., and Thompson, R.C.A.Activities of several benzimidazoles and tubulin inhibitors against Giardia spp. in vitroAntimicrob. Agents Chemother.37(2)328-331(1993) 2.Suter, C., MÜller-Doblies, U.U., Hatt, J.-M., et al.Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazoleVet. Rec. 148(15)478-480(2001) 3.Aleyasin, H., Karuppagounder, S.S., Kumar, A., et al.Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulinAntioxid. Redox Signal.22(2)121-134(2015)
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *