K252d |
| Katalog-Nr.GC47522 |
A PKC inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 105114-22-5
Sample solution is provided at 25 µL, 10mM.
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K252d is an indolocarbazole alkaloid found in Nocardiopsis.1 It is a PKC inhibitor that inhibits PKC isolated from rat brain (IC50 = 350 nM). It also inhibits calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart (IC50 = 46.2 µM).
1.Nakanishi, S., Matsuda, Y., Iwahashi, K., et al.K-252b, c and d, potent inhibitors of protein kinase C from microbial originJ. Antibiot. (Tokyo) 39(8)1066-1071(1986)
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