Trospium-d8 (chloride) (Synonyms: Relaspium-d8) |
| Katalog-Nr.GC48209 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Trospium-d8 is intended for use as an internal standard for the quantification of trospium by GC- or LC-MS. Trospium is an antagonist of muscarinic (M) receptors (Kis = 0.50-2.3 nM for human M1-5 recombinant receptors, respectively).1 Formulations containing antimuscarinics, including trospium, are used to manage overactive bladder by relieving urgency, frequency, and incontinence.1,2,3
1.Hegde, S.S.Muscarinic receptors in the bladder: From basic research to therapeuticsBr. J. Pharmacol.147(2)S80-S87(2006) 2.Maggiore, U.L.R., Salvatore, S., Alessandri, F., et al.Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in femalesExpert Opin.Drug Metab.Toxicol.8(11)1387-1408(2012) 3.Michel, M.C., and de la Rosette, J.J.M.C.H.Role of muscarinic receptor antagonists in urgency and nocturiaBJU Int.96(Suppl 1)37-42(2005)
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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