TunR1 |
| Katalog-Nr.GC48213 |
An antibiotic and derivative of tunicamycin
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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TunR1 is an antibiotic and derivative of tunicamycin .1 It is active against B. subtilis (MIC = 0.3 µg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G against B. subtilis when used at a concentration of 0.4 µg/ml. TunR1 (5 µg/ml) is cytotoxic to MDA-MB-231 breast cancer cells and non-cancerous CHO cells. Unlike tunicamycin, TunR1 does not inhibit glycosylation in a protein N-glycosylation assay.
1.Price, N.P., Hartman, T.M., Li, J., et al.Modified tunicamycins with reduced eukaryotic toxicity that enhance the antibacterial activity of β-lactamsJ. Antibiot. (Tokyo)70(11)1070-1077(2017)
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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