Tryptoquivaline D (Synonyms: Nortryptoquivaline, NSC 292204) |
| Katalog-Nr.GC48442 |
Tryptoquivalin D ist ein Pilzmetabolit von Aspergillus fumigatus.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 60676-56-4
Sample solution is provided at 25 µL, 10mM.
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Tryptoquivaline D is a fungal metabolite that has been found in Neosartorya siamensis and has anticancer activity.1,2 It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells when used at a concentration of 150 µM.1 Tryptoquivaline D (1-100 µM), alone or in combination with doxorubicin , reduces the viability of A549 lung cancer cells.2
1.Prata-Sena, M., Ramos, A.A., Buttachon, S., et al.Cytotoxic activity of secondary metabolites from marine-derived fungus Neosartorya siamensis in human cancer cellsPhytother. Res.30(11)1862-1871(2016) 2.Ramos, A.A., Castro-Carvalho , B., Prata-Sena, M., et al.Can marine-derived fungus Neosartorya siamensis KUFA 0017 extract and its secondary metabolites enhance antitumor activity of doxorubicin• An in vitro survey unveils interactions against lung cancer cellsEnviron. Toxicol.35(4)507-517(2020)
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