Neosartoricin |
| Katalog-Nr.GC48484 |
A prenylated tricyclic polyketide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1421941-29-8
Sample solution is provided at 25 µL, 10mM.
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Neosartoricin is a prenylated tricyclic polyketide produced in A. fumigatus and N. fischeri overexpressing the N. fischeri polycyclic prenyltransferase (pcPTase) nsc gene cluster.1 It inhibits the proliferation of anti-CD3 and anti-CD28-stimulated mouse spleen T cells (IC50 = 2.99 μM).
1.Chooi, Y.-H., Fang, J., Liu, H., et al.Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungiOrg. Lett.15(4)780-783(2013)
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