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CAY10781

Katalog-Nr.GC49094

An NRP-1/VEGF-A interaction inhibitor

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CAY10781 Chemische Struktur

Cas No.: 1210360-87-4

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10 mg
83,00 $
Auf Lager
50 mg
336,00 $
Auf Lager
100 mg
630,00 $
Auf Lager
250 mg
1.470,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1 It inhibits the interaction by 43% when used at a concentration of 12.5 µM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.

1.Perez-Miller, S., Patek, M., Moutal, A., et al.In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike proteinbioRxiv308783(2020)

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