N-Acetyl-L-thyroxine (Synonyms: N-acetyl-L-T4, N-Acetylthyroxine, N-acyl-L-T4) |
| Katalog-Nr.GC49802 |
A thyroid hormone derivative
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 26041-51-0
Sample solution is provided at 25 µL, 10mM.
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N-Acetyl-L-thyroxine is an acetylated derivative of L-thyroxine .1 It only weakly binds to thyroxine-binding globulin (TBG) in isolated human serum with a relative binding affinity of 25 compared with L-thyroxine. N-Acetyl-L-thyroxine is also a potential impurity in commercial preparations of L-thyroxine.2
1.Snyder, S.M., Cavalieri, R.R., Goldfine, I.D., et al.Binding of thyroid hormones and their analogues to thyroxine-binding globulin in human serumJ. Biol. Chem.251(21)6489-6494(1976) 2.Panmanad, D., Joshi, M.S., Patil, R., et al.Synthesis and characterization of potential impurities in levothyroxineChem. Sci. Trans.5(4)1082-1089(2016)
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