CAY10668 |
| Katalog-Nr.GC40705 |
Di-, tri-, and tetramethoxystilbenes potently inhibit cytochrome P450 1B1 (CYP1B1), an isoform involved in estrogen metabolism and implicated in hormone-mediated cancers.
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Sample solution is provided at 25 µL, 10mM.
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Di-, tri-, and tetramethoxystilbenes potently inhibit cytochrome P450 1B1 (CYP1B1), an isoform involved in estrogen metabolism and implicated in hormone-mediated cancers. CAY10668 is a 4-hydroxylated form of 2,2',6'-trimethoxy-trans-stilbene. The 4-methoxylated form of the same trans-stilbenoid inhibits CYP1B1 (IC50 = 1.77 nM), suggesting that this compound may also be an inhibitor of CYP1B1.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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