Ceramide (hydroxy) (bovine spinal cord) |
| Katalog-Nr.GC52489 |
A sphingolipid
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.1 This product contains ceramide molecular species with primarily 2-hydroxy C24:0 and 2-hydroxy C18:0 fatty acyl chains. [Matreya, LLC. Catalog No. 1323]
1.Ogretmen, B., Pettus, B.J., Rossi, M.J., et al.Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A547 human lung adenocarcinoma cell lineJ. Biol. Chem.277(15)12960-12969(2002)
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