Choline hydroxide |
Katalog-Nr.GC67532
One-Click Copy Product Info
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Cholinhydroxid ist ein mit Cholin-Wasserstoff oxidiertes Derivat und eine starke organische Base, die als Standardalkali verwendet werden kann, um den pH-Wert des Mediums einzustellen. Cholin ist ein oral wirksamer Nährstoff, dient als wichtiger Bestandteil von Lecithin und Sphingomyelin, fördert den Fettstoffwechsel.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 123-41-1
Sample solution is provided at 25 µL, 10mM.
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Choline hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism [1][2][3].
Choline hydroxide can be used as the standard alkaline, and (0.5 M) results pHo shifts rapidly to 7.59 in a sucrose medium (pH at 7.08)[1].
Choline hydroxide (0.1-0.5 g/mL), together with organic carboxylic acids, makes preparation of ionic liquids, which is used for prepare a ionic liquid-reverse micelle drug-carrying delivery system and involves in epidermal desensitization research[2].
[1]. Mitchell P, et al. Estimation of membrane potential and pH difference across the cristae membrane of rat liver mitochondria. Eur J Biochem. 1969 Feb;7(4):471-84.
[2]. Ding Y, et al. An ionic liquid-reverse micelle drug delivery system for epidermal desensitization therapy and its preparation method and application: China, CN113975224. 2022-01-28.
[3]. Wang F, et al. Short communication: Effects of dietary deoiled soy lecithin supplementation on circulating choline and choline metabolites, and the plasma phospholipid profile in Holstein cows fed palm fat. J Dairy Sci. 2021 Feb;104(2):1838-1845.
| Cas No. | 123-41-1 | SDF | |
| Formula | C5H15NO2 | M.Wt | 121.18 |
| Löslichkeit | >100mg/ml in Water | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 8.2522 mL | 41.2609 mL | 82.5219 mL |
| 5 mM | 1.6504 mL | 8.2522 mL | 16.5044 mL |
| 10 mM | 825.2 μL | 4.1261 mL | 8.2522 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: 44 wt. % in H2O Appearance: A solution in Water
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)