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Dilmapimod (SB-681323)

Katalog-Nr.GC31697

Dilmapimod (SB-681323) (SB-681323) ist ein potenter p38-MAPK-Inhibitor, der mÖglicherweise EntzÜndungen bei chronisch obstruktiven Lungenerkrankungen unterdrÜckt.

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Dilmapimod (SB-681323) Chemische Struktur

Cas No.: 444606-18-2

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10mM (in 1mL DMSO)
262,00 $
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1mg
131,00 $
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5mg
261,00 $
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10mg
378,00 $
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20mg
493,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Dilmapimod (SB-681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.

Dilmapimod (SB-681323) potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression[1].

[1]. Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100.

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