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DOTATATE acetate

Katalog-Nr.GC61528

DOTATATE-Acetat ist ein DOTA-konjugiertes Peptid. DOTATATE-Acetat kann mit Radionukliden fÜr die Positronen-Emissions-Tomographie (PET)-Bildgebung und die Peptidrezeptor-Radionuklidtherapie (PRRT) markiert werden.

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DOTATATE acetate Chemische Struktur

Cas No.: 177943-89-4

Größe Preis Lagerbestand Menge
5 mg
232,00 $
Auf Lager
10 mg
389,00 $
Auf Lager
25 mg
695,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide therapy (PRRT)[1][2][3][4].

177Lu-DOTATATE shows excellent antitumor effects in rats[1].

[1]. Jong M, et, al. Combination radionuclide therapy using 177Lu- and 90Y-labeled somatostatin analogs. J Nucl Med. 2005 Jan;46 Suppl 1:13S-7S. [2]. Gains JE, et, al. 68Ga-DOTATATE and 123I-mIBG as imaging biomarkers of disease localisation in metastatic neuroblastoma: implications for molecular radiotherapy. Nucl Med Commun. 2020 Aug 10. [3]. Breeman WAP, et, al. Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities. Eur J Nucl Med Mol Imaging. 2003 Jun;30(6):917-20. [4]. Reubi JC, et, al. Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use. Eur J Nucl Med. 2000 Mar;27(3):273-82.

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