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Erythromycin (Synonyms: NSC 55929)

Katalog-Nr.GC12946

Erythromycin ist ein Makrolid-Antibiotikum, das von Aktinomyceten Streptomyces erythreus mit einem breiten Spektrum an antimikrobieller AktivitÄt produziert wird.

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Erythromycin Chemische Struktur

Cas No.: 114-07-8

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10mM (in 1mL DMSO)
27,00 $
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500mg
25,00 $
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1g
29,00 $
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5g
44,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].

Erythromycin inhibits growth of P. falciparum with IC50 and IC90 values of 58.2 μM and 104.0 μM, respectively[1].

References:
[1]. Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89.
[2]. Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28.

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