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Eudesmin

Katalog-Nr.GC61941

Eudesmin ((-)-Eudesmin) beeintrÄchtigt die adipogene Differenzierung durch Hemmung des S6K1-Signalwegs.

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Eudesmin Chemische Struktur

Cas No.: 526-06-7

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5 mg
495,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities[1].

Treatment of mesenchymal stem cells (MSCs) with Eudesmin (20, 40, and 80µM) disturbs adipogenesis via suppression of S6K1 signaling pathway. Eudesmin treatment inhibits activation and nuclear translocation of S6K1. S6K1-mediated phosphorylation of H2B at serine 36 (H2BS36p) is reduced upon Eudesmin treatment[1].

References:
[1]. Ki Hong Nam, et al. Eudesmin Impairs Adipogenic Differentiation via Inhibition of S6K1 Signaling Pathway. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1148-1153.

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