FABPs ligand 6 (Synonyms: MF6) |
| Katalog-Nr.GC65322 |
FABPs-Ligand 6 (MF6) ist ein FABP5- und FABP7-Inhibitor mit KD-Werten von 874 nM bzw. 20 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with KD values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research[1].
FABPs ligand 6 (MF6) rescues mitochondrial function by blocking voltagedependent anion channel (VDAC)-1-dependent mitochondrial macropore formation induced by psychosine in KG-1C cells, a FABP5- mediated injury[1].
MF 6 (1 mg/kg; i.g.; daily for 4 weeks) improves the severity of EAE (experimental autoimmune encephalomyelitis) and attenuates oxidative levels and the inflammatory response[1].
[1]. Cheng A, et al. A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models. EBioMedicine. 2021 Oct;72:103582.
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