Friedelin |
| Katalog-Nr.GC60169 |
Friedelin wird aus den BlÄttern von Maytenus ilicifolia (Mart) isoliert.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 559-74-0
Sample solution is provided at 25 µL, 10mM.
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Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79 μM and 6.16 μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54 μM and 18.02 μM, respectively[1].
[1]. Wei J, et al. In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. Pharm Biol. 2018 Dec;56(1):363-367.
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