Gastric Inhibitory Peptide (22-51) (human) (trifluoroacetate salt) |
| Katalog-Nr.GC90561 |
Ein pro-atherogenes Peptid.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Gastric inhibitory peptide (GIP) (22-51) is a pro-atherogenic 30-amino acid peptide corresponding to residues 22-51 of the GIP precursor protein proGIP that has been found in human plasma.1 It induces IκB-α degradation and NF-κB nuclear translocation in macrophage-differentiated THP-1 cells and isolated human aortic endothelial cells when used at a concentration of 1 µM. In vivo, GIP (22-51) increases atherosclerotic lesion area and plaque formation in ApoE-/- mice.
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