ATP-polyamine-biotin |
| Katalog-Nr.GC35422 |
ATP-Polyamin-Biotin, das erste zellgÄngige ATP-Analogon, ist ein effizientes Kinase-Cosubstrat.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1800401-93-7
Sample solution is provided at 25 µL, 10mM.
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ATP-polyamine-biotin is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM.ATP-polyamine-biotin is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. APB is cell-permeable and nontoxic at low mM concentrations, with cell penetration and labeling dependent on the polyamine linker.
[1]. Fouda AE, Pflum MK. A Cell-Permeable ATP Analogue for Kinase-Catalyzed Biotinylation. Angew Chem Int Ed Engl. 2015 Aug 10;54(33):9618-21.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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