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DC41

Katalog-Nr.GC35817

DC41 ist ein DC1-Derivat. DC1, ein vereinfachtes Analogon von CC-1065, ist ein AntikÖrperkonjugat aus zytotoxischen DNA-Alkylatoren zur gezielten Behandlung von Krebs.

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DC41 Chemische Struktur

Cas No.: 1354787-69-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer[1][2].

[1]. Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82. [2]. Kovtun YV, et al. Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen. Cancer Res. 2006 Mar 15;66(6):3214-21.

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