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Jionoside A1

Katalog-Nr.GC36369 Copy One-Click Copy Product Info

Aus Radix Rehmanniae Praeparata isoliertes Jionosid A1 zeigt eine dosisabhÄngige immunverstÄrkende AktivitÄt und besitzt mÄßige SchutzaktivitÄten gegenÜber H2O2-behandelten SH-SY5Y-Zellen.

Products are for research use only. Not for human use. We do not sell to patients.

Jionoside A1 Chemische Struktur

Cas No.: 120444-60-2

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Sample solution is provided at 25 µL, 10mM.



Description of Jionoside A1

Jionoside A1 isolated from Radix Rehmanniae Praeparata displays dose dependent immune-enhancement activity and possesses moderate protective activities on H2O2-treated SH-SY5Y cells[1].

[1]. Shen L, et al. Identification of bioactive ingredients with immuno-enhancement and anti-oxidative effects from Fufang-Ejiao-Syrup by LC-MS(n) combined with bioassays. J Pharm Biomed Anal. 2016 Jan 5;117:363-71.

Chemical Properties of Jionoside A1

Cas No. 120444-60-2 SDF
Canonical SMILES COC1=C(O)C=CC(/C=C/C(O[C@H]2[C@@H]([C@H]([C@H](OCCC3=CC(O)=C(O)C=C3)O[C@@H]2CO[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)O)O[C@@]5([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O5)O)O)=O)=C1
Formula C36H48O20 M.Wt 800.75
Löslichkeit Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Jionoside A1

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.2488 mL 6.2441 mL 12.4883 mL
5 mM 249.8 μL 1.2488 mL 2.4977 mL
10 mM 124.9 μL 624.4 μL 1.2488 mL
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In vivo Formulation Calculator (Clear solution) of Jionoside A1

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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