Coumarin-3-carboxylic Acid |
| Katalog-Nr.GC38238 |
Cumarin-3-carbonsÄure (2-Oxochromen-3-carbonsÄure) ist eine wichtige Ausgangsverbindung fÜr die Synthese von Cumarinen, die aufgrund ihrer vielfÄltigen biologischen AktivitÄten als Naturstoffe bekannt sind. Lanthanid-Komplexe von Cumarin-3-CarbonsÄure zeigen eine antiproliferative AktivitÄt gegenÜber der K-562-Zelllinie.
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Cas No.: 531-81-7
Sample solution is provided at 25 µL, 10mM.
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Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line[1][2].
[1]. Aimin Song, et al. A convenient synthesis of coumarin-3-carboxylic acids via Knoevenagel condensation of Meldrum's acid with ortho-hydroxyaryl aldehydes or ketones. Tetrahedron Letters. 2003 Feb;44(9): 1755-1758. [2]. Kostova I, et al. New Samarium(III), Gadolinium(III), and Dysprosium(III) Complexes of Coumarin-3-Carboxylic Acid as Antiproliferative Agents. Met Based Drugs. 2007;2007:15925.
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