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Eurycomalactone

Katalog-Nr.GC38548

Eurycomalacton ist ein aktives Quassinoid, das aus Eurycoma longifolia Jack isoliert werden konnte.

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Eurycomalactone Chemische Struktur

Cas No.: 23062-24-0

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1mg
156,00 $
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5mg
466,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Eurycomalactone is a natural product found in Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor, with an IC50 of 0.5 μM. Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα/β and IκBα[1].

[1]. Malainer C, et al. Eurycomalactone Inhibits Expression of Endothelial Adhesion Molecules at a Post-Transcriptional Level. J Nat Prod. 2017 Dec 22;80(12):3186-3193.

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