Hellebrigenin |
| Katalog-Nr.GC64786 |
Hellebrigenin, eines der zu den kardioaktiven Steroiden gehÖrenden Bufadienolide, wird aus der traditionellen chinesischen Medizin Venenum Bufonis isoliert. Hellebrigenin induziert DNA-SchÄden und G2/M-Arrest des Zellzyklus. Hellebrigenin lÖst die mitochondrienvermittelte Apoptose aus.
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Cas No.: 465-90-7
Sample solution is provided at 25 µL, 10mM.
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Hellebrigenin, one of bufadienolides belonging to cardioactive steroids, is isolated from traditional Chinese medicine Venenum Bufonis. Hellebrigenin induces DNA damage and cell cycle G2/M arrest. Hellebrigenin triggers mitochondria-mediated apoptosis.
[1]. Deng LJ, et al. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Chem Biol Interact. 2014 Aug 5;219:184-94.
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