(-)-Hydroxycitric acid lactone |
| Katalog-Nr.GC63570 |
(-)-HydroxyzitronensÄurelacton (Garcinialacton) ist ein Mittel gegen Fettleibigkeit und ein beliebtes NahrungsergÄnzungsmittel zur Gewichtsabnahme.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 27750-13-6
Sample solution is provided at 25 µL, 10mM.
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(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis[1][2].
(-)-Hydroxycitric acid lactone (1000-3000mg/kg; fed for a period of 4 weeks) significantly decreases body weight at 2000 and 3000 mg/kg in chicken[2].
[1]. Jena BS, et al. Chemistry and biochemistry of (-)-hydroxycitric acid from Garcinia. J Agric Food Chem. 2002 Jan 2;50(1):10-22.
[2]. Han J, et al. (-)-Hydroxycitric acid reduced fat deposition via regulating lipid metabolism-related geneexpression in broiler chickens. Lipids Health Dis. 2016 Feb 24;15:37.
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