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ICI 192,605

Katalog-Nr.GC11080 Copy One-Click Copy Product Info

ICI 192.605 ist ein potenter TXA2R (Thromboxan A2-Rezeptor)-Antagonist als Zellsignalgeber für Prostaglandin.

Products are for research use only. Not for human use. We do not sell to patients.

ICI 192,605 Chemische Struktur

Cas No.: 117621-64-4

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1mg
49,00 $
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5mg
143,00 $
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10mg
257,00 $
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25mg
562,00 $
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Sample solution is provided at 25 µL, 10mM.



Chemical Properties of ICI 192,605

Cas No. 117621-64-4 SDF
Chemical Name (Z)-6-((2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl)hex-4-enoic acid
Canonical SMILES ClC1=CC=CC=C1[C@H]2O[C@@H](C3=CC=CC=C3O)[C@@H](C/C=C\CCC(O)=O)CO2
Formula C22H23ClO5 M.Wt 402.87
Löslichkeit DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 25 mg/ml Storage Desiccate at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of ICI 192,605

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.4822 mL 12.411 mL 24.8219 mL
5 mM 496.4 μL 2.4822 mL 4.9644 mL
10 mM 248.2 μL 1.2411 mL 2.4822 mL
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In vivo Formulation Calculator (Clear solution) of ICI 192,605

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 16 reference(s) in Google Scholar.)

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