IRAK-4 protein kinase inhibitor 2 |
| Katalog-Nr.GC62583 |
IRAK-4-Proteinkinase-Inhibitor 2 (Verbindung 1) ist ein potenter Inhibitor von Interleukin-1 (IL-1)-Rezeptor-assoziierter Kinase-4 (IRAK-4) mit einem IC50 von 4 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 301675-24-1
Sample solution is provided at 25 µL, 10mM.
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IRAK-4 protein kinase inhibitor 2 (compound 1) is a potent inhibitor of interleukin-1 (IL-1) receptor-associated kinase-4 (IRAK-4), with an IC50 of 4 μM. IRAK-4 protein kinase inhibitor 2 can be used for the research of inflammatory and immune-related conditions or disorders[1].
IRAK-4 protein kinase inhibitor 2 (compound 1) also inhibits IRAK-1, with an IC50 of <10 μM[1].
[1]. Powers JP, et, al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.
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