m-PEG7-Amine |
| Katalog-Nr.GC65845 |
m-PEG7-Amin ist ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann. m-PEG7-Amin ist ein spaltbarer ADC-Linker, der bei der Synthese von AntikÖrper-Wirkstoff-Konjugaten (ADCs) verwendet wird.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 170572-38-0
Sample solution is provided at 25 µL, 10mM.
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m-PEG7-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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