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N-desethyl Amodiaquine (hydrochloride)

Katalog-Nr.GC44344

N-Desethyl Amodiaquin (Hydrochlorid) ist der wichtigste biologisch aktive Metabolit von Amodiaquin.

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N-desethyl Amodiaquine (hydrochloride) Chemische Struktur

Cas No.: 79049-30-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

References:
[1]. Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82.

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