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Nitrofurazone-13C,15N2

Katalog-Nr.GC71623 Copy One-Click Copy Product Info

Nitrofurazone-13C,15N2 (Nitrofural-13C,15N2) ist das 13C und 15N markierte Nitrofurazon.

Products are for research use only. Not for human use. We do not sell to patients.

Nitrofurazone-13C,15N2 Chemische Struktur

Cas No.: 1217220-85-3

Größe Preis Lagerbestand Menge
1mg
140,00 $
Auf Lager
5mg
342,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.



Description of Nitrofurazone-13C,15N2

Nitrofurazone-13C,15N2 (Nitrofural-13C,15N2) is the 13C and 15N labled Nitrofurazone . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants. Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. Uroosa, et al. Effects of nitrofurazone on ecosystem function in marine environments: A case study on microbial fauna. Mar Pollut Bull. 2022 Nov;184:114216.

Chemical Properties of Nitrofurazone-13C,15N2

Cas No. 1217220-85-3 SDF
Formula C513CH6N215N2O4 M.Wt 201.12
Löslichkeit Storage
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Nitrofurazone-13C,15N2

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.9722 mL 24.8608 mL 49.7216 mL
5 mM 994.4 μL 4.9722 mL 9.9443 mL
10 mM 497.2 μL 2.4861 mL 4.9722 mL
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In vivo Formulation Calculator (Clear solution) of Nitrofurazone-13C,15N2

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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