Obidoxime dichloride (Synonyms: Toxogonin) |
| Katalog-Nr.GC63305 |
Obidoximdichlorid ist ein Nicht-Vollspektrum-Oxim-Wirkstoff und kann als Gegenmittel fÜr eine Organophosphat-Nervenkampfstoff-Vergiftung verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 114-90-9
Sample solution is provided at 25 µL, 10mM.
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Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated[1].
Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD50 of 57.7 mg/kg after administration of sarin, and it reduces reduces acute toxicity of sarin was evaluated[1].
[1]. Kassa J,et al. A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.Toxicol Mech Methods. 2015 Mar;25(3):229-33.
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