PfDHODH-IN-1 |
| Katalog-Nr.GC64567 |
PfDHODH-IN-1 ist ein Analogon des aktiven Metaboliten von Leflunomid.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 183945-55-3
Sample solution is provided at 25 µL, 10mM.
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PfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity[1][2].
[1]. Li SL, et al. 3D-QSAR studies on a series of dihydroorotate dehydrogenase inhibitors: analogues of the active metabolite of leflunomide. Int J Mol Sci. 2011;12(5):2982-93.
[2]. Hou X, et al. QSAR study on the antimalarial activity of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors. SAR QSAR Environ Res. 2016;27(2):101-24.
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