Poly(2-hydroxyethyl methacrylate) (MW 20000) |
Katalog-Nr.GC61903
One-Click Copy Product Info
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Poly(2-hydroxyethylmethacrylat) (MW 20000) ist eines der wichtigsten Hydrogele in der Welt der Biomaterialien.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 25249-16-5
Sample solution is provided at 25 µL, 10mM.
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Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of drug and etc[1].
Poly(2-hydroxyethyl methacrylate) (PolyHEMA) retains moisture content similar to the live tissue and is resistant to degradation and absorption by the host cells. It can be easily manufactured in a variety of shapes and can be readily sterilized[1]. Proliferation rate of the cells that had been cultured on Poly(2-hydroxyethyl methacrylate) is reduced; Poly(2-hydroxyethyl methacrylate) does not induce cell death in the hRPE cultures. Human retinal pigment epithelium (RPE) cells cultured on Poly(2-hydroxyethyl methacrylate) formed many giant spheroid colonies. The giant colonies are re-cultured and the presence of retinal progenitor markers and markers of hRPE cells are detected in cell cultures on Poly(2-hydroxyethyl methacrylate)[1].
References:
[1]. Fatemeh Nazemroaya, et al. Induced Retro-Differentiation of Human Retinal Pigment Epithelial Cells on PolyHEMA. J Cell Biochem. 2017 Oct;118(10):3080-3089.
| Cas No. | 25249-16-5 | SDF | |
| Canonical SMILES | OCCOC(C(C)(C)CC)=O | ||
| Formula | M.Wt | 20000(Average) | |
| Löslichkeit | Storage | 4°C, away from moisture | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 50 μL | 250 μL | 500 μL |
| 5 mM | 10 μL | 50 μL | 100 μL |
| 10 mM | 5 μL | 25 μL | 50 μL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)