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PRE084 (Synonyms: 2-(4-Morpholinethyl) 1-phenylcyclohexanecarboxylate hydrochloride)

Katalog-Nr.GB40331 Copy One-Click Copy Product Info

PRE084 (138847-85-8) is an agonist of the σ receptor with selectivity for the σ1 subtype (IC50's: σ1 = 2.2nM, σ2 = 13091nM). PRE-084 has demonstrated neuroprotective/restorative effects in brain injury and neurodegenerative conditions.

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PRE084 Chemische Struktur

Cas No.: 138847-85-5

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5mg
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Sample solution is provided at 25 µL, 10mM.



Description of PRE084

PRE084 (138847-85-8) is an agonist of the σ receptor with selectivity for the σ1 subtype (IC50's: σ1 = 2.2nM, σ2 = 13091nM). PRE-084 has demonstrated neuroprotective/restorative effects in brain injury and neurodegenerative conditions.

Chemical Properties of PRE084

Cas No. 138847-85-5 SDF
Überlieferungen 2-(4-Morpholinethyl) 1-phenylcyclohexanecarboxylate hydrochloride
Formula C19H27NO3?? HCl M.Wt 353.89
Löslichkeit Storage
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of PRE084

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8257 mL 14.1287 mL 28.2574 mL
5 mM 565.1 μL 2.8257 mL 5.6515 mL
10 mM 282.6 μL 1.4129 mL 2.8257 mL
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In vivo Formulation Calculator (Clear solution) of PRE084

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for PRE084

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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