Quin C1 |
| Katalog-Nr.GC50212 |
Quin C1 ist ein hochspezifischer und wirksamer Agonist fÜr den Formylpeptidrezeptor 2 (FPR2/ALX).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 786706-21-6
Sample solution is provided at 25 µL, 10mM.
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Potent and selective FPR2 agonist (EC50 = 15 nM). Induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Anti-inflammatory.
Zhou et al (2007) Pharmacological characterization of a novel nonpeptide antagonist for formyl peptide receptor-like 1. Mol.Pharmacol. 72 976 PMID:17652444 |Corminboeuf et al (2014) FPR2/ALXR agonists and the resolution of inflammation. J.Med.Chem. 58 537 PMID:25365541
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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